Endocrine Abstracts

Background: The role of EGFR, HER2, PDGF-A and the axis PDGF-B/ PDGFR-β in the pathogenesis of pituitary adenomas and their correlation with the tumoral immunoprofile are poorly understood.Materials and methods: The study included 92 cases. We used morphological stains, immunohistochemistry and molecular methods to characterize the tumors.Results: 33.33% of adenomas showed a positive immunohistochemical reaction for HER2- with...